PGF and Cytokines	Cell0 Sources	Function and Effects
PDGF (AA-BB-AB)	Platelets, endothelial cells, macrophages, smooth muscle cells	Mitogenic for mesenchymal cells and osteoblasts, stimulates chemotaxis and mitogenesis in fibroblast/ glial/smooth muscle cells, regulates collagenase secretion and collagen synthesis, stimulates macrophage and neutrophil chemotaxis
TGF (α–β)	Macrophages, Tlymphocytes, keratinocytes	Stimulates undifferentiated mesenchymal cell proliferation; regulates endothelial, fibroblastic, and osteoblastic mitogenesis; regulates collagen synthesis and collagenase secretion; regulates mitogenic effects of other growth factors; stimulates endothelial chemotaxis and angiogenesis; inhibits macrophage and lymphocyte proliferation
VEGF	Platelets, macrophages, keratinocytes, endothelial cells	Increases angiogenesis and vessel permeability, stimulates mitogenesis for endothelial cells
EGF	Platelets, macrophages, monocytes	Proliferation of keratinocytes, fibroblasts, stimulates mitogenesis for endothelial cells
(a-b)-FGF	Platelets, macrophages, mesenchymal cells, chondrocytes, osteoblasts	Promotes growth and differentiation of chondrocytes and osteoblasts; mitogenic for mesenchymal cells, chondrocytes, and osteoblasts
CTGF	Platelets, fibroblasts	Promotes angiogenesis, cartilage regeneration, fibrosis, and platelet adhesion
IGF-1	Platelets, plasma, epithelial cells, endothelial cells, fibroblasts, osteoblasts, bone matrix	Chemotactic for fibroblasts and stimulates protein synthesis. Enhances bone formation by proliferation and differentiation of osteoblasts
HGF	Platelets, mesenchymal cells	Regulates cell growth and motility in epithelial/endothelial cells, supporting epithelial repair and neovascularization during wound healing
KGF	Fibroblasts, mesenchymal cells	Regulates epithelial migration and proliferation
Ang-1	Platelets, neutrophils	Induces angiogenesis stimulating migration and proliferation of endothelial cells. Supports and stabilizes blood vessel development via the recruitment of pericyte
PF4	Platelets	Calls leucocytes and regulates their activation. Microbiocidal activities
SDF-1α	Platelets, endothelial cells, fibroblasts	Calls CD34+ cells, induces their homing, proliferation and differentiation into endothelial progenitor cells stimulating angiogenesis. Calls mesenchymal stem cells and leucocytes
TNF	Macrophages, mast cells, T lymphocytes	Regulates monocyte migration, fibroblast proliferation, macrophage activation, angiogenesis

PGF and Cytokines	Cell0 Sources	Function and Effects
PDGF (AA-BB-AB)	Platelets, endothelial cells, macrophages, smooth muscle cells	Mitogenic for mesenchymal cells and osteoblasts, stimulates chemotaxis and mitogenesis in fibroblast/ glial/smooth muscle cells, regulates collagenase secretion and collagen synthesis, stimulates macrophage and neutrophil chemotaxis
TGF (α–β)	Macrophages, Tlymphocytes, keratinocytes	Stimulates undifferentiated mesenchymal cell proliferation; regulates endothelial, fibroblastic, and osteoblastic mitogenesis; regulates collagen synthesis and collagenase secretion; regulates mitogenic effects of other growth factors; stimulates endothelial chemotaxis and angiogenesis; inhibits macrophage and lymphocyte proliferation
VEGF	Platelets, macrophages, keratinocytes, endothelial cells	Increases angiogenesis and vessel permeability, stimulates mitogenesis for endothelial cells
EGF	Platelets, macrophages, monocytes	Proliferation of keratinocytes, fibroblasts, stimulates mitogenesis for endothelial cells
(a-b)-FGF	Platelets, macrophages, mesenchymal cells, chondrocytes, osteoblasts	Promotes growth and differentiation of chondrocytes and osteoblasts; mitogenic for mesenchymal cells, chondrocytes, and osteoblasts
CTGF	Platelets, fibroblasts	Promotes angiogenesis, cartilage regeneration, fibrosis, and platelet adhesion
IGF-1	Platelets, plasma, epithelial cells, endothelial cells, fibroblasts, osteoblasts, bone matrix	Chemotactic for fibroblasts and stimulates protein synthesis. Enhances bone formation by proliferation and differentiation of osteoblasts
HGF	Platelets, mesenchymal cells	Regulates cell growth and motility in epithelial/endothelial cells, supporting epithelial repair and neovascularization during wound healing
KGF	Fibroblasts, mesenchymal cells	Regulates epithelial migration and proliferation
Ang-1	Platelets, neutrophils	Induces angiogenesis stimulating migration and proliferation of endothelial cells. Supports and stabilizes blood vessel development via the recruitment of pericyte
PF4	Platelets	Calls leucocytes and regulates their activation. Microbiocidal activities
SDF-1α	Platelets, endothelial cells, fibroblasts	Calls CD34+ cells, induces their homing, proliferation and differentiation into endothelial progenitor cells stimulating angiogenesis. Calls mesenchymal stem cells and leucocytes
TNF	Macrophages, mast cells, T lymphocytes	Regulates monocyte migration, fibroblast proliferation, macrophage activation, angiogenesis

Advantages of PRP for Hair Treatment

PRP therapy has given many amazing results in the hair treatment. Few of the advantages of PRP treatment are summarised here.

Natural and Autologous: PRP therapy utilizes the patient’s own blood. So there are minimal risks involved in this treatment such as the risk of allergic reactions or rejection.
Non-Invasive: Unlike surgical hair restoration procedures, PRP is a minimally invasive treatment with little to no downtime.
Potential for Improved Hair Quality: PRP may not only stimulate hair growth but also enhance the overall quality and thickness of existing hair.

Disadvantages of PRP

Limited Scientific Evidence: While some studies suggest positive outcomes, more research is needed to establish the long-term effectiveness of PRP for hair treatment.
Variable Results: Individual responses to PRP can vary, and not all patients may experience the same degree of improvement.
Mild Discomfort: Patients may experience mild discomfort during the blood draw or injection Process. But it is tolerable to all patients.

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PRP (platelet-rich plasma) treatment is a popular option in Bangladesh for those looking for a non-surgical solution to hair loss. Bangladesh is famous for its advanced medical tourism sector, especially hair restoration services. PRP treatment involves drawing a small amount of the patient’s blood, processing it to concentrate platelets, and injecting it into the scalp to stimulate hair growth.

Here are some reasons why Bangladesh is a preferred destination for PRP treatment

Expertise and Technology: Many clinics in Bangladesh are equipped with the latest technology and experienced professionals who specialize in hair restoration.
Cost-Effectiveness: Compared to many Western countries, Bangladesh offers competitive prices for PRP and other hair loss treatments.
High success rate: Bangladesh clinics are known for their high quality and patient satisfaction, ensuring effective results.
Medical tourism packages: Many clinics provide comprehensive packages that include accommodation, transportation and personal care.

PRP - Platelet Rich Plasma

PRP Treatment in Bangladesh by HFHG

At Hair Free Hair Grow Bangladesh, we offer PRP (Platelet-Rich Plasma) treatment for hair loss, an advanced and effective solution to stimulate hair growth. PRP treatment uses your body’s own platelets, which are rich in growth factors, to rejuvenate hair follicles, increase hair thickness and reduce hair loss.

Our clinic in Dhaka is equipped with the latest technology, and our experienced team ensures that each treatment is tailored to meet your specific needs. PRP treatment is a minimally invasive procedure with minimal downtime, making it a popular choice for those looking for non-surgical hair restoration options.

Role of PRP in Hair Treatment

Platelet Rich Plasma or PRP therapy is the bread butter of Hair

It’s more popular nowadays as a non-invasive safe and natural solution for various medical and aesthetic concerns.

It is the best treatment option available for Hair Loss

Non-invasive treatments

What is PRP?

Its your own blood cell that involves separation of concentrated form of platelets from the patient’s own whole blood with the help of high speed stable centrifuse machine at 3500 rpm speed

The red blood cells, white blood cells and platelets are separated from the plasma the growth factors found in the platelet-rich plasma are then injected into the scalp under local anesthesia to promote hair growth.

PRP (Platelet Rich Plasma) is a medical procedure to repair regenerate and regrowth your damaged hair

PRP contains several different growth factors and other cytokines that can play a crucial role in the human body’s natural healing process, containing growth factors that stimulate tissue repair and regeneration.

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Types of PRP:

Routine PRP: Where blood is collected in regular ACD tubes and only PRP cells is there

Biotin PRP: Tube is impregnated with Biotin cells which acts as a supplement to the PRP, thus improving the efficacy of PRP treatment as biotin is known to hair protein so it helps to control hair fall and stimulate hair growth.

GFC: The tube is impregnated with a derived form of extra growth factor concentrate, GFC treatment is the most advanced method of PRP and acts as faster recovery with double strength

Regular PRP :

The PRP tubes contain a thixotropic gel that separates the supernatant plasma from the cellular components, allowing to obtain autologous plasma of a powerful therapeutic effect.
There are three general categories of preparation of PRP based on its leukocyteand fibrin content
Leukocyte-rich PRP (L-PRP), leukocyte reduced PRP (P-PRP; leukocyte reduced or pure PRP), leukocyte platelet-rich fibrin. The platelets collected in PRP can be activated by the addition of thrombinor calcium chloride, which induces the release of the mentioned factors from alpha granules

The growth factors and other cytokines present in PRP include:

Treatment Plan

Regular PRP therapy Needs 3-4 sessions which are done at intervals of one month.
Regular PRP is also used as a maintenance treatment for hair loss and hair thinning at intervals of every 3 months

Biotin PRP

Known for its role in promoting hair growth and strength. When combined with PRP therapy, the results are even more impressive.
PRP encourages the activation of hair follicles, while biotin provides the necessary nutrients for healthier, thicker hair. Together, they create an optimal environment for regrowth

Treatment Plan

Biotin PRP therapy Needs 3-5 sessions which are done at intervals of one month.
Biotin PRP used as booster PRP and for maintaining and stimulating hair regrowth

GFC (Growth Factor concentrate) Therapy

GFC Is a pure, safe, highly concentrated growth factor concoction prepared from patients’ blood.

In GFC treatment, injecting higher concentrations of growth factors better than only platelets are extracted from the patient’s own whole blood.
GFC is safe, pure, acellular, and completely autologous.
GFC is injected directly into the scalp or skin and your own growth factors are delivered in high concentration to promote hair growth and improve hair thinning

Treatment Plan

GFC therapy Needs 3-4 sessions which are done at intervals of one month.

Benefits of GFC therapy

No platelet wastage during the procedure and a higher concentration of growth factors are extracted and injected directly into the scalp
Completely acellular and reduced risk of inflammation and pain
GFC serum extracted by the procedure has excellent stability for 8 hours at room temperature.
Very simple and safe procedure with minor risk of any complication.

is PRP Suitable
for me?

How does GFC differ from PRP?

PRP involves extracting the patient’s blood, separating the platelets, and injecting the entire serum into the scalp.
The injected platelets then gradually release the growth factors that provide the intended results.
Alpha and dense granules are the two main granule kinds found in platelets.
Alpha granules contain specific proteins, such as VEGF, EGF, and IGF, that are necessary for hair regrowth. While During the process of PRP, both types of granules are released.
But in the GFC process, we utilize certain tubes with a patented activator that only activates the platelets’ alpha granules. As a result, we get the plasma that contains special proteins which are higher concentrations of growth factors that help to promote hair development.

How to Perform PRP for Hair Treatment?

Stepwise procedure of PRP Treatment for hair growth and hair loss as below.

1. Blood Collection: A small amount of blood is drawn from the patient, typically from the arm. It is collected in a small tube which is designed specifically for this purpose. Usually, 10 to 20 ml of blood is sufficient.

2. Centrifugation: The collected blood is then processed in a centrifuge machine for PRP tube rotates at 3500 rpm for 7-10 min to separate the platelets from other blood components. In this process, Red Blood Cells and plasma are separated. Plasma is rich in platelets. It is called PRP

3. PRP Extraction: After the centrifugation process the concentrated PRP is drawn in syringes and prepared for injection

4. Preparation of site: First clean the target area with anti septic solution and than give local anaesthesia to make it painless

5. PRP Injection: The PRP is injected into specific areas of the scalp using very fine needles.

A partial list of PRP-based growth factors and platelet cytokines with their cell sources.

PGF and Cytokines	Cell0 Sources	Function and Effects
PDGF (AA-BB-AB)	Platelets, endothelial cells, macrophages, smooth muscle cells	Mitogenic for mesenchymal cells and osteoblasts, stimulates chemotaxis and mitogenesis in fibroblast/ glial/smooth muscle cells, regulates collagenase secretion and collagen synthesis, stimulates macrophage and neutrophil chemotaxis
TGF (α–β)	Macrophages, Tlymphocytes, keratinocytes	Stimulates undifferentiated mesenchymal cell proliferation; regulates endothelial, fibroblastic, and osteoblastic mitogenesis; regulates collagen synthesis and collagenase secretion; regulates mitogenic effects of other growth factors; stimulates endothelial chemotaxis and angiogenesis; inhibits macrophage and lymphocyte proliferation
VEGF	Platelets, macrophages, keratinocytes, endothelial cells	Increases angiogenesis and vessel permeability, stimulates mitogenesis for endothelial cells
EGF	Platelets, macrophages, monocytes	Proliferation of keratinocytes, fibroblasts, stimulates mitogenesis for endothelial cells
(a-b)-FGF	Platelets, macrophages, mesenchymal cells, chondrocytes, osteoblasts	Promotes growth and differentiation of chondrocytes and osteoblasts; mitogenic for mesenchymal cells, chondrocytes, and osteoblasts
CTGF	Platelets, fibroblasts	Promotes angiogenesis, cartilage regeneration, fibrosis, and platelet adhesion
IGF-1	Platelets, plasma, epithelial cells, endothelial cells, fibroblasts, osteoblasts, bone matrix	Chemotactic for fibroblasts and stimulates protein synthesis. Enhances bone formation by proliferation and differentiation of osteoblasts
HGF	Platelets, mesenchymal cells	Regulates cell growth and motility in epithelial/endothelial cells, supporting epithelial repair and neovascularization during wound healing
KGF	Fibroblasts, mesenchymal cells	Regulates epithelial migration and proliferation
Ang-1	Platelets, neutrophils	Induces angiogenesis stimulating migration and proliferation of endothelial cells. Supports and stabilizes blood vessel development via the recruitment of pericyte
PF4	Platelets	Calls leucocytes and regulates their activation. Microbiocidal activities
SDF-1α	Platelets, endothelial cells, fibroblasts	Calls CD34+ cells, induces their homing, proliferation and differentiation into endothelial progenitor cells stimulating angiogenesis. Calls mesenchymal stem cells and leucocytes
TNF	Macrophages, mast cells, T lymphocytes	Regulates monocyte migration, fibroblast proliferation, macrophage activation, angiogenesis

PGF and Cytokines	Cell0 Sources	Function and Effects
PDGF (AA-BB-AB)	Platelets, endothelial cells, macrophages, smooth muscle cells	Mitogenic for mesenchymal cells and osteoblasts, stimulates chemotaxis and mitogenesis in fibroblast/ glial/smooth muscle cells, regulates collagenase secretion and collagen synthesis, stimulates macrophage and neutrophil chemotaxis
TGF (α–β)	Macrophages, Tlymphocytes, keratinocytes	Stimulates undifferentiated mesenchymal cell proliferation; regulates endothelial, fibroblastic, and osteoblastic mitogenesis; regulates collagen synthesis and collagenase secretion; regulates mitogenic effects of other growth factors; stimulates endothelial chemotaxis and angiogenesis; inhibits macrophage and lymphocyte proliferation
VEGF	Platelets, macrophages, keratinocytes, endothelial cells	Increases angiogenesis and vessel permeability, stimulates mitogenesis for endothelial cells
EGF	Platelets, macrophages, monocytes	Proliferation of keratinocytes, fibroblasts, stimulates mitogenesis for endothelial cells
(a-b)-FGF	Platelets, macrophages, mesenchymal cells, chondrocytes, osteoblasts	Promotes growth and differentiation of chondrocytes and osteoblasts; mitogenic for mesenchymal cells, chondrocytes, and osteoblasts
CTGF	Platelets, fibroblasts	Promotes angiogenesis, cartilage regeneration, fibrosis, and platelet adhesion
IGF-1	Platelets, plasma, epithelial cells, endothelial cells, fibroblasts, osteoblasts, bone matrix	Chemotactic for fibroblasts and stimulates protein synthesis. Enhances bone formation by proliferation and differentiation of osteoblasts
HGF	Platelets, mesenchymal cells	Regulates cell growth and motility in epithelial/endothelial cells, supporting epithelial repair and neovascularization during wound healing
KGF	Fibroblasts, mesenchymal cells	Regulates epithelial migration and proliferation
Ang-1	Platelets, neutrophils	Induces angiogenesis stimulating migration and proliferation of endothelial cells. Supports and stabilizes blood vessel development via the recruitment of pericyte
PF4	Platelets	Calls leucocytes and regulates their activation. Microbiocidal activities
SDF-1α	Platelets, endothelial cells, fibroblasts	Calls CD34+ cells, induces their homing, proliferation and differentiation into endothelial progenitor cells stimulating angiogenesis. Calls mesenchymal stem cells and leucocytes
TNF	Macrophages, mast cells, T lymphocytes	Regulates monocyte migration, fibroblast proliferation, macrophage activation, angiogenesis

Advantages of PRP for Hair Treatment

PRP therapy has given many amazing results in the hair treatment. Few of the advantages of PRP treatment are summarised here.

Natural and Autologous: PRP therapy utilizes the patient’s own blood. So there are minimal risks involved in this treatment such as the risk of allergic reactions or rejection.
Non-Invasive: Unlike surgical hair restoration procedures, PRP is a minimally invasive treatment with little to no downtime.
Potential for Improved Hair Quality: PRP may not only stimulate hair growth but also enhance the overall quality and thickness of existing hair.

Disadvantages of PRP

Limited Scientific Evidence: While some studies suggest positive outcomes, more research is needed to establish the long-term effectiveness of PRP for hair treatment.
Variable Results: Individual responses to PRP can vary, and not all patients may experience the same degree of improvement.
Mild Discomfort: Patients may experience mild discomfort during the blood draw or injection Process. But it is tolerable to all patients.

Send Your Queries

Here are some reasons why Bangladesh is a preferred destination for PRP treatment

Expertise and Technology: Many clinics in Bangladesh are equipped with the latest technology and experienced professionals who specialize in hair restoration.
Cost-Effectiveness: Compared to many Western countries, Bangladesh offers competitive prices for PRP and other hair loss treatments.
High success rate: Bangladesh clinics are known for their high quality and patient satisfaction, ensuring effective results.
Medical tourism packages: Many clinics provide comprehensive packages that include accommodation, transportation and personal care.

Advantages of PRP for Hair Treatment

Disadvantages of PRP

Book Consultation

PRP Treatment in Bangladesh

PRP - Platelet Rich Plasma

PRP Treatment in Bangladesh by HFHG

Role of PRP in Hair Treatment

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How does GFC differ from PRP?

Advantages of PRP for Hair Treatment

Disadvantages of PRP

Book Consultation

PRP Treatment in Bangladesh

Book Consultation